Marie Lamothe;Didier Junquero;Yves Rival;Michel Perez
发明人:
Michel Perez,Marie Lamothe,Didier Junquero,Yves Rival
申请号：
US13254473
公开号：
US09187438B2
申请日:
2010.03.02
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The object of the present invention is benzothiazine derivatives having the capability of inhibiting 11β-HSD1 not only at an enzymatic level but also at a cell level. The compounds of the present invention are of general formula (I). Wherein notably R1 represents a hydrogen or OR1 represents an ester or an ether. R2 represents a naphthyl or a 1,2,3,4-tetrahydro-naphthalene or a biphenyl or phenyl pyridine or a substituted phenyl. R3 represents a methyl or ethyl； R4 and R′4 represent a hydrogen.
