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DERIVATIVES OF BENZOTHIAZINES,PREPARATION THEREOF AND APPLICATION THEREOF AS DRUGS
专利权人:
发明人:
PEREZ MICHEL,LAMOTHE MARIE,JUNQUERO DIDIER,RIVAL YVES
申请号:
IN7244/DELNP/2011
公开号:
IN2011DN07244A
申请日:
2011.09.21
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The object of the present invention is benzothiazine derivatives having the capability of inhibiting 11ß-HSD1 not only at an enzymatic level but also at a cell level. The compounds of the present invention are of general formula (I). Wherein notably R1 represents a hydrogen or OR1 represents an ester or an ether. R2 represents a naphthyl or a 1, 2, 3, 4-tetrahydro-naphthalene or a biphenyl or phenyl pyridine or a substituted phenyl. R3 represents a methyl or ethyl R4 and R4 represent a hydrogen.
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