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Utilisation de dérivés de coumarine pour la préparation de médicaments prévus pour traiter des maladies cutanées
专利权人:
Université Pierre et Marie Curie - Paris 6
发明人:
申请号:
EP11305931.5
公开号:
EP2545916A1
申请日:
2011.07.15
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention relates to a compound of formula (I)wherein n equals 0 or 1, and wherein, if n=1, Z represents O or S, R1 represents at least one group chosen among the group consisting of hydrogen, a linear or branched, saturated or not, C1-C7 alkyl, substituted, or not, by a halogen, a group -CH2-O-CO-R5 wherein R5 is chosen among a hydrogen atom, and a linear or branched, saturated or not, C1-C7 alkyl, substituted or not by at least one halogen, and an amine, and R2 is chosen among the group consisting of a linear or branched, saturated or not C1-C7 alkyl, a C3-C6 cycloalkyl, an aryl group, and an heteroaryl group for its use for the treatment of pathologies involving an excess of activity of at least one member of the kallikrein family.
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