您的位置: 首页 > 农业专利 > 详情页

Use of coumarin derivatives for the preparation of drugs for the treatment of skin diseases
专利权人:
Université Pierre et Marie Curie (Paris 6)
发明人:
REBOUD, RAVAUX,YERROUM, EL AMRI,TAN, Xiao,QIN, Lixian,PAGANO, Maurice,HOVNANIAN, Alain,FURIO, Laetitia,PIROTTE, Bernard
申请号:
ES12733783
公开号:
ES2632798T3
申请日:
2012.07.13
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Compound of formula (I-1b): ** Formula ** in which - Z represents O or S, - R1 represents at least one group selected from the group consisting of: - a hydrogen - a linear C1-C7 alkyl or branched, saturated or not, preferably a methyl group, substituted, or not, with a halogen selected from Cl, F, I and Br, - a linear or branched C1-C7 alkyl, saturated or not, preferably a methyl group, substituted with a hydroxyl or a -O-R12 group, wherein R12 is a linear or branched C1-C7 alkyl, saturated or not, preferably a hydroxyl, - a -CH2-O-CO-R5 group, in which R5 is selected between a hydrogen atom and a linear or branched C1-C7 alkyl, saturated or not, substituted or not with at least one halogen selected from Cl, F, I and Br, - a group -O-R13, in which R13 is selects between hydrogen and a linear or branched C1-C7 alkyl, saturated or not, R13 being preferably a hydrogen, - an amine ** Formula ** or a salt thereof, in which R3 and R4, independently from each other, hydrogen and a linear or branched C1-C5 alkyl, saturated or not, are selected and - a group ** Formula ** or a salt thereof, in which R9 and R10, independently of each other other, are selected from: - hydrogen, - a linear or branched C1-C5 alkyl, saturated or not, - -CO-R5, wherein R5 is selected from a hydrogen atom, and a linear or branched C1-C7 alkyl , saturated or not, substituted or not with at least one halogen selected from Cl, F, I and Br, - -SO2-R11 in which R11 is a linear or branched C1-C7 alkyl, saturated or not, - R'1 represents a group selected from hydrogen and -O-R14, wherein R14 is selected from hydrogen and a linear or branched C1-C7 alkyl, saturated or not, R14 being preferably a hydrogen, R'1 being preferably a hydrogen, with the provided that R'1 represents hydrogen when R1 does not represent a group -O-R13, and - R2 is selected from the group consisting of: - an alq linear or branched C1-C7 uyl, saturated or not, preferably a C1-C3 alkyl, - a C3-C6 cycloalkyl, preferably a C4-C6 cycloalk
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充