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Compuestos de piperidina, composición farmacéutica que comprende los mismos y su uso
专利权人:
SK HOLDINGS CO.; LTD.
发明人:
CHUNG, COO-MIN,JUN, HYUNG-JIN,KIM, JIN-SUNG,KIM, HUI-HO,MIN, HYE-KYUNG,KIM, YONG-GIL,CHOI, JONG-GIL,KIM, HONGWOOK
申请号:
ES09820735
公开号:
ES2428101T3
申请日:
2009.10.13
申请国别(地区):
ES
年份:
2013
代理人:
摘要:
A piperidine compound selected from compounds of structural formula (I): ** ** Formula and pharmaceutically acceptable salts thereof wherein m is an integer of 1 or 2 n is an integer from 0 to 2 A is selected from a phenyl group and a benzimidazole group, wherein the phenyl group is substituted with one or more groups independently selected from hydrogen, an alkyl group linear or branched C1-C6 alkyl, a C1-C6 linear or branched, an amino group, and a halogen, and the benzimidazole group group is substituted with one or more groups independently selected from hydrogen, a C1-C6 linear or branched, a C1-C6 linear or branched, a group C3-C7 cyclic alkyl, amino, halogen and oxo X is hydroxy or OCONR1R2 wherein R1 and R2 are independently selected from hydrogen, a C1-C6 linear or branched, a benzyl group, and a cyclic compound or a 5- to 7-membered substituted with one or more groups independently selected from a C1 to C6 alkyl, and R1 and R2 form a heterocyclic ring of 5 to 7 members together with a nitrogen atom to which they are attached and B is selected from a phenyl group, a phenoxy group, a thienyl group and a naphthyl group, wherein the phenyl group, phenoxy group, the thienyl group or naphthyl substituted with one or more groups independently selected from from hydrogen, halogen, nitro, cyano, methanesulfonyl, trifluoromethyl, trifluoromethoxy, difluoromethoxy, phenyl, a linear alkyl group or branched C1-C6 alkoxy and linear or branched C1-C6 group.Un compuesto de piperidina seleccionado de entre los compuestos de fórmula estructural (I):**Fórmula** y sales farmacéuticamente aceptables del mismo en la que m es un número entero de 1 ó 2 n es un número entero de 0 a 2 A se elige de entre un grupo fenilo y un grupo bencimidazol, en la que el grupo fenilo está sustituido con uno o más grupos elegidos independientemente de entre hidrógeno, un grupo alquilo C1-C6 lineal o ramificado, un grupo alcoxi C1-C6 lineal o ramificado, un grupo amino, y un halógeno, y el grupo b
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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