A medicine which contains as an active ingredient a benzothiazin-3-one compound represented by the formula (1): (wherein n is 3 or 4； R represents ethyl or hydrogen； and R1 represents halogeno, alkoxy, haloalkyl, or haloalkoxy) or a pharmaceutically acceptable salt thereof. It is useful as a therapeutic or preventive agent for arthrosis deformans, chondrodegenerative diseases such as chronic articular rheumatism, cancers, gingivitis, etc. Also provided are an intermediate for the compound and a process for producing the compound.本發明係提供一種含有苯幷噻嗪-3-酮化合物或其藥學上可接受之鹽以作為有效成分之醫藥品、其製造中間物以及其製造方法，上述苯幷噻嗪-3-酮化合物可用於作為變形性關節症、慢性關節風濕症等軟骨變性疾病、癌症以及牙齦炎等的治療劑或預防劑，且用式(1)：(式中，n表示3或4，R表示乙基或氫原子，R1表示鹵素原子、烷氧基、鹵烷基或鹵烷氧基。)表示。
