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Process for producing fused heterocyclic derivative and production intermediate thereof
专利权人:
キッセイ薬品工業株式会社
发明人:
相内 孝幸,河西 潔,米窪 滋,大野 孝介,曽根原 順一,小林 眞
申请号:
JP2014535565
公开号:
JP6268093B2
申请日:
2013.09.11
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
Provided are an industrially useful method for producing a fused-heterocyclic derivative or salt thereof which is useful as a preventive agent, therapeutic agent, reproductive adjustment agent, contraceptive, ovulation-inducing agent, or sex-hormone-dependent-cancer-post-operation-recurrence preventive agent which target sex-hormone-dependent diseases and the like such as prostate enlargement, uterine myoma, endometriosis, uterine fibroma, precocious puberty, amenorrhea, premenstrual syndrome, dysmenorrhea, polycystic ovary syndrome, lupus erythematosus, hypertrichosis, dwarfism, sleep disorders, acne, baldness, Alzheimer's disease, infertility, irritable bowel syndrome, prostate cancer, uterine cancer, ovarian cancer, breast cancer, and pituitary tumors; and a production intermediate thereof. The present invention makes it possible to produce a compound or salt thereof represented by general formula (A) in high yield and purity by using a compound represented by general formula (D) (R1 and R2 represent identical or different C1-6 alkyl groups, and R3 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, or a nitro group).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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