The present invention relates capable of labeling anti-CDH3 antibody with a radioactive isotope. Furthermore, the present invention provides methods and pharmaceutical compositions comprising anti-CDH3 antibody as an active ingredient. CDH3 because it is strongly expressed in cells of pancreatic cancer liver cancer, lung cancer, colon cancer, prostate cancer, breast cancer, or gastric cancer, the present invention is liver pancreatic cancer, lung cancer, colon cancer, prostate cancer, breast cancer, or stomach cancer, It is useful in the treatment of cancer.本発明は、放射性同位体で標識可能な抗CDH3抗体に関する。さらに、本発明は、有効成分として抗CDH3抗体を含む方法および薬学的組成物を提供する。CDH3は膵臓癌、肺癌、結腸癌、前立腺癌、乳癌、胃癌、または肝臓癌の細胞において強く発現されるので、本発明は、膵臓癌、肺癌、結腸癌、前立腺癌、乳癌、胃癌、または肝臓癌の治療において有用である。