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From 8 - amino - 2 - oxo - 1.3 - Grabarsky, IT's The Wrong Guy spiro [4.5] - decane
专利权人:
GRÜNENTHAL GMBH
发明人:
SCHRDER, WOLFGANG,LINZ, KLAUS,KOCH, THOMAS,JOSTOCK, RUTH,RATCLIFFE, PAUL,WEGERT, ANITA,KLESS, ACHIM,KOENIGS, REN MICHAEL,KHNERT, SVEN
申请号:
ARP170100094
公开号:
AR107359A1
申请日:
2017.01.13
申请国别(地区):
AR
年份:
2018
代理人:
摘要:
8-amino-2-oxo-1, 3-diazo-helix - [4.5] - Dean, phase and use in medicine, including pain treatment 1. characteristic 1: compound (1) with general formula characteristic,R¹ and R² independently of each other mean -H; -C₁₋₆-alkyl, linear or branched, saturated or unsaturated, unsubstituted or substituted with one, two, three or four substituents selected independently from each other from the group consisting of -F, -Cl, -Br, - I, -OH, -OCH₃,-CN y CO CHa. A 3-12 person, saturated or unsaturated, unsaturated or unsaturated circulating chemical device, not replaced or replaced by one, two, three or four substitutes independently selected from a group consisting of - F, - Cl, - Br, - I, - Oh, - och-8323;-CN and -CO₂CH₃;a. 3-12 members of the bicycle unit can be selected through - c833213126 - asphalt connection;a. A nonreplaced linear or treelike, saturated or unsaturated, or unsaturated, or unsaturated, or unsaturated, or unsaturated, 3-12 member heterocyclic chemical device, which is not replaced or replaced by one, two, three or four substitutes independently selected from a group consisting of F, Cl, Br, I, oh, oc832323;-CN and -CO₂CH₃;wherein said 3-12 membered heterocycloalkyl unit is optionally connected via -C₁₋₆-alkylene-,linear or branched, saturated or unsaturated, unsubstituted; or R¹ and R² together with the nitrogen atom to which they are attached form a ring and signify - (CH₂) ₃₋₆-;- (CH) -O- (CH) -o - (CH) -NRA- (CH) -where RA means -H or -C₁₋₆-alkyl, linear or branched, saturated or unsaturated, unsubstituted or substituted with one, two, three or four substituents selected independently of one another from the group consisting of -F, - Cl, -Br and -I; R³ means -C₁₋₆-alkyl, linear or branched, saturated or unsaturated, unsubstituted, monosubstituted or polysubstituted; a 3-12 membered, saturated or unsaturated, unsubstituted, monosubstituted or polysubstituted cycloalkyl unit; wherein said 3-12 membered cycloalkyl unit is optionally connected via -C₁₋₆-
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