PERICAS-BRONDO, Miguel Angel,TORRENS-JOVER, Antonio,YENES-MINGUEZ, Susana,GARCIA GRANDA, Carmen,CUEVAS CORDOBES, Félix
申请号:
ES07724754
公开号:
ES2573004T3
申请日:
2007.04.30
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Substituted bicyclic tetrahydropyrrole compounds of the general formula (I) ** Formula ** in which R 1 represents an alkyl-aryl group in which any of the alkyl and / or aryl group is optionally substituted by one or more substituents independently selected from the group consisting of a C1-4 alkyl group, a linear or branched C1-6 alkoxy group, F, Cl, I, Br, CF3, CH2F, CHF2, CN, OH, SH, NH2, (C>; = O) R ' , SR ', SOR', SO2R ', NHR', NRR '' in which R 'and optionally R' 'independently represents for each substituent a linear or branched C1-6 alkyl group; a benzhydryl group, which is optionally substituted by one or more substituents independently selected from the group consisting of a C1-4 alkyl group, a linear or branched C1-6 alkoxy group, F, Cl, I, Br, CF3, CH2F, CHF2 , CN, OH or SH; in which the link between Z and Y is saturated (Y-Z); representing Y CH and representing Z CH-R6; or in which the link between Z and Y is unsaturated (Y>; = Z) representing Y CH and Z representing a C-R6 group; R6 represents a branched or unbranched C1-6 alkyl group, which is optionally substituted by one or more substituents independently selected from the group consisting of an alkyl group F, Cl, I, Br, CF3, CH2F, CHF2, CN, OH, SH, NH2; an aryl group, which is optionally substituted by one or more substituents independently selected from the group consisting of a C1-4 alkyl group; an optionally at least mono-substituted phenyl group; a linear or branched C1-6 alkoxy group; F, Cl, I, Br, CF3, CH2F, CHF2, CN, OH, SH, NH2, (C>; = O) R ', SR', SOR ', SO2R', N (C>; = O) -OR ' , NHR ', NR'R' 'in which R' and optionally R '' for each substituent independently represent a linear or branched C1-6 alkyl group; an alkyl-aryl group in which the alkyl group and / or the aryl group is optionally substituted by one or more substituents independently selected from the group consisting of a C1-4 alkyl group, a linear or branched C1-6 alkoxy group, F , Cl, I, Br, CF3, CH2F, CHF2, CN, OH, SH,