In the woman of age of menopause front and back, it combined with the royal jello and vitamin E optionally, as a active ingredient for producing the medicine for dealing with the disease which it is related to normal hormone fluctuation, in the pollen and option water solubility of the pistil and/or use of the composition which includes the liposoluble cytoplasm sol extract.閉経前後の年齢の女性における、正常のホルモン変動に関連する疾病の処置のための薬剤の製造のための、活性成分として、任意にロイヤルゼリーおよびビタミンEと組み合わせた、花粉および任意にめしべの水溶性および/または脂溶性細胞質ゾル抽出物を含む組成物の使用。