A biomass-derived dietary supplement comprising an acetate salt, a hemicellulose-derived sweetener, and cellulose is provided. The formulation may originate from treatment of biomass, by converting acetic acid (from biomass) to an acetate salt and combining it with a hemicellulose-based sweetener such as xylitol and inert, non-digestive cellulose. This is formed into a powder, crystal, pill or capsule to be delivered orally as a dietary supplement. Supplemental minerals and vitamins may be added. A process for producing a biomass-derived dietary supplement is also disclosed.