Gregory KAPP,Laura SERWER,Natacha LE MOAN,Stephen P.L. CARY
申请号：
US14759635
公开号：
US20160185839A1
申请日:
2013.01.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H-NOX proteins as radiosensitizers for the treatment of brain cancers.
