GIBBONS, Paul,HANAN, Emily,LIU, Wendy,LYSSIKATOS, Joseph P.,MAGNUSON, Steven R.,MENDONCA, Rohan,PASTOR, Richard,RAWSON, Thomas E.,SIU, Michael,ZAK, Mark E.,ZHOU, Aihe,ZHU, Bing-Yan,HURLEY, Christopher
申请号:
DK10794815
公开号:
DK2448941T3
申请日:
2010.07.02
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.