GIBBONS, Paul,HANAN, Emily,LIU, Wendy,LYSSIKATOS, Joseph P.,MAGNUSON, Steven R.,MENDONCA, Rohan,PASTOR, Richard,RAWSON, Thomas E.,SIU, Michael,ZAK, Mark E.,ZHOU, Aihe,ZHU, Bing-Yan
申请号:
AU2017228672
公开号:
AU2017228672A1
申请日:
2017.09.14
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2017228672A120171005.pdf#####ABSTRACT A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R 2 and R3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and 5 a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed. H N N H N H 0 H H R2 0 287 7088938_1 (GHMatters) P89201.AU.1 SHEILAB