GIBBONS, PAUL,ZHOU, AIHE,ZAK, MARK E.,ZHU, BING-YAN,HANAN, EMILY,LIU, WENDY,LYSSIKATOS, JOSEPH P.,MAGNUSON, STEVEN R.,MENDONCA, ROHAN,PASTOR, RICHARD,RAWSON, THOMAS E.,SIU, MICHAEL
申请号:
MYPI 2011006384
公开号:
MY160156A
申请日:
2010.07.02
申请国别(地区):
MY
年份:
2017
代理人:
摘要:
A COMPOUND OF FORMULA I, ENANTIOMERS, DIASTERIOMERS, TAUTOMERS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, WHEREIN R1, R2 AND R3 ARE DEFINED HEREIN, ARE USEFUL AS INHIBITORS OF ONE OR MORE JANUS KINASES. A PHARMACEUTICAL COMPOSITION THAT INCLUDES A COMPOUND OF FORMULA I AND A PHARMACEUTICALLY ACCEPTABLE CARRIER, ADJUVANT OR VEHICLE, AND METHODS OF TREATING OR LESSENING THE SEVERITY OF A DISEASE OR CONDITION RESPONSIVE TO THE INHIBITION OF A JANUS KINASE ACTIVITY IN A PATIENT ARE DISCLOSED.