GIBBONS, Paul,HANAN, Emily,LYSSIKATOS, Joseph P.,MAGNUSON, Steven R.,MENDONCA, Rohan,PASTOR, Richard,RAWSON, Thomas E.,SIU, Michael,ZAK, Mark E.,ZHOU, Aihe,ZHU, Bing-Yan,LIU, Wendy
申请号：
AU2015255320
公开号：
AU2015255320A1
申请日:
2015.11.13
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
#$%^&*AU2015255320A120151203.pdf#####ABSTRACT A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R, R 2 and R are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of 5 Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed. H N- N H R1/ N H 0 NH R2 R3 10 C:\NRPortbl\GHMatters\SONIAM\7100427_1.docx 9/11/15
