LAPPE, Susan E.,PHILLIPS, Darren C.,HILL, Oliver,THIEMANN, Meinolf,GIEFFERS, Christian,BUCHANAN, Fritz G.
申请号：
PE2016002016
公开号：
PE20170299A1
申请日:
2015.04.23
申请国别(地区):
PE
年份:
2017
代理人:
摘要：
It refers to the activator protein of a foaming receptor related to tumor necrosis factor (TRAIL), which is characterized by a peptide containing amino acid sequence No. 19, including three soluble Terrell domains and one Fc fragment. You also mean a composer This protein is not added in large quantities and is suitable for therapeutic purposes, such as cancer treatmentSe refiere a una proteina agonista de los receptores de ligando inductor de apoptosis relacionado con el factor de necrosis tumoral (TRAIL) caracterizada porque comprende un polipeptido que tiene una secuencia de aminoacidos de SEQ ID N° 19 que comprende tres dominios de TRAIL solubles y un fragmento Fc. Tambien se refiere a una composicion. Dicha proteina no forma agregados de forma sustancial y son apropiadas para aplicaciones terapeuticas tal como el tratamiento de cancer
