FIELD: chemistry.SUBSTANCE: invention relates to condensed heterocyclic derivative of formula (I), selected from structures A, B, C, D and E, where R1 is selected from (1-4C)alkyl； (3-6C)cycloalkyl； indanyl, optionally substituted with halogen； phenyl, optionally substituted with one-three substituents, independently selected from halogen, cyano, (1-4C)alkyl, optionally substituted with one or several fluorine atoms, (1-4C)alkoxy, optionally substituted with one or several fluorine atoms； pyridyl, optionally substituted with one halogen atom； Z represents linker group -W-(C-alkylene)-T-, where W is bound with R1 and is selected from bond, -O-, -S-, -SO-, -NH-,-CH=CH-, -C≡C- and trans-cyclopropyle≠ n represents integer number from 0 to 2, T is bound with phenylene fragment and is selected from bond, -O-, -S-, -SO-, -NH-, -CO-, -C=C-, -C≡C- and trans-cyclopropyle≠ R2 represents H or one or two substituents, independently selected from halogen, (1-4C)alkyl, optionally substituted with one-three halogen atoms, or (104C)alkoxy； X is selected from C or N； if X represents C, R3 is selected from H and (1-4C)alkyl, in other case R3 is absent； Y is selected from NH, O and S； R4 represents (1-4C)alkylene-R5 where one or several carbon atoms in alkylene group can be independently substituted with one or two halogen atoms or (CH), with formation of cyclopropyl part, R5 represents -COOH. The invention also relates to pharmaceutically acceptable salts of formula (I) compounds, pharmaceutical composition, containing formula (I) compounds, and application of formula (I) compounds for medication manufacturing.EFFECT: formula compounds, demonstrating properties of receptor S1P agonists.24 cl, 1 dwg, 1 tblИзобретение относится к конденсированному гетероциклическому производному формулы (I), выбранной из структур А, В, С, D и Е, где R1 выбран из (1-4С)алкила； (3-6С)циклоалкила； инданила, необязательно замещенного галогеном； фенила, необязательно замещенного одним - тремя заместителями
