PARK Chan Khee (KR),ПАРК Чан Хее (KR),LI Sang Khvi (KR),ЛИ Санг Хви (KR),IM Dzunkhvan (KR),ИМ Дзунхван (KR),LI Soon Ok (KR),ЛИ Соон Ок (KR),KIM Khoe Moon (KR),КИМ Хое Моон (KR),MOON Sung Khyun (KR),МО
申请号：
RU2015153063
公开号：
RU0002681849C2
申请日:
2014.06.03
申请国别(地区):
RU
年份:
2019
代理人:
摘要：
FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula:n which A represents a saturated or unsaturated C5-6 carbocycle or a 5-10-membered heterocycle； B is a benzene or a 5-12-membered heterocycle containing 1-3 nitrogen atoms； C is a benzene, a 5-12-membered heterocycle or a C3-6 carbocycle； Y represents -C(= O)- associated with X2 or X5； X1 is -O-, -S-, -S(=O)-, -S(=O)2- or -N(W1)-； X2 is a carbon atom bound to Y, or -N =, -NH-, -C(W2)= or -CH(W2)-, which is not associated with Y； X3 and X4 independently represent a carbon or nitrogen atom； X5 is a carbon atom bound to Y, or -CH=, which is not bound to Y； wherein the 5-membered ring including X1-X5 is aromatic or non-aromatic； W is a hydrogen, halogen or C1-6 alkyl； W1 is a hydrogen, C1-6 alkyl, C1-6 alkoxycarbonyl or 5-8-membered heterocyclyl-C1-4 alkyl； W2 is a hydrogen, halogen, C1-6 alkyl or 5-8-membered heterocyclyl-C1-4 alkyl； L is -(CR9R10)m-, -(CR9R10)m-O-, -NH-, -N(C1-6 alkyl)-, -S(=O)2-, -C(=O)-, -C(=CH2)- or C3-7 cycloalkylene, wherein m is an integer from 0 to 3 and R9 and R10 independently represent a hydrogen, halogen or C1-6 alkyl； R1 is nitro, amino, C1-6 alkylsulfonyl, halogenC1-6 alkoxy or any of the following structural formulas i) to iv): i) , ii) , iii) and iv) ； R2 is a hydrogen, halogen, nitro, amino, C1-6alkoxy, halogenC1-6alkoxy, C1-6 alkylsulfonyl or 5- or 6-membered heterocycloalkyl； R3 is a hydrogen, halogen, cyano, C1-6 alkyl, halogen1-6 alkyl, cyanoC1-6 alkyl, C1-6 alkylcarbonyl, C1-6 alkoxy, halogen C1-6 alkoxy, cyanoC1-6 alkoxy, C1-6 alkylamino, diC1-6 alkylamino, C1-6 alkylthio, C1-6 alkylaminocarbonyl, diC1-6 alkylaminocarbonyl, C2-8 alkynyl, C6-10 aryl, halogenC6-10 aryl, 5-10-membered heterocyclyl or 5-10-membered heterocyclylcarbonyl, wherein the heterocyclyl part may be substituted by one to three substituents； R4 is a hydrogen, halogen, hydroxy, cyano, nitro, amino, oxo, aminosulfonyl, sulfonylamido, C1-6 alkylamino, C1-6 alkyl, halogenC1-6 alkyl, cyanoC1-6 a
