An anti-IL-22 antibody or antibody fragment that binds to both human IL-22 and a mammalian IL-22 as well as modified anti-IL-22 antibodies and antibody fragments. Pharmaceutical compositions and kits comprising the antibody or antibody fragment are also provided. Also provided are methods for treatment of various IL-22 mediated conditions and diseases.本發明提供結合至人類IL-22及哺乳動物IL-22兩者之抗IL-22抗體或抗體片段以及經修飾抗IL-22抗體及抗體片段。亦提供包含該抗體或抗體片段之醫藥組合物及套組。亦提供用於治療各種IL-22介導之病狀及疾病之方法。
