Christopher W. Grote,Joseph P. McClurg,John E. Johnson, Jr.,Sarah M. Farris
申请号：
US13491676
公开号：
US09296699B2
申请日:
2012.06.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides compositions of 6-amino morphinan compounds and process for their synthesis. In particular, the processes provide for the reductive amination of 6-keto morphinans by catalytic transfer hydrogenation, to produce 6-amino morphinan compounds, which are epimerically and/or diastereomerically enriched.
