2,4-SUBSTITUTED NUCLEOSIDES AS ANTIVIRAL AGENTS

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专利权人:

GILEAD PHARMASSET LLC

发明人:

DU, JINFA,SOFIA, MICHAEL, J

申请号：

NZ60148608

公开号：

NZ601486A

申请日:

2008.11.17

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

601486 Disclosed is the use of azido and purine or pyrimidine substituted tetrahydrofurans in the manufacture of a medicament for treating hepatitis B virus (HBV). Examples of the compounds are: 9-((2R,3S,4S,5R)-5-azido-3-ethyl-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol 4-amino-1-((2R,3S,4S,5R)-5-azido-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one and 9-((2R,3S,4S,5R)-5-azido-4-hydroxy-5-(hydroxymethyl)-3-(trifluoromethyl)tetrahydrofuran-2-yl)-9Hpurin-6-ol.

来源网站：

中国工程科技知识中心

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