FORMULACIO ANTICUERPO ANTI-A4

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专利权人:

INC.;MILLENNIUM PHARMACEUTICALS

发明人:

DILUZIO, WILLOW,TRUONG, NOBEL T.,VARGA, CSANAD M.,PALANIAPPAN, VAITHIANATHAN,BROWN, JASON,FOX, IRVING H.,SCHOLZ, CATHERINE

申请号：

CR20130677

公开号：

CR20130677A

申请日:

2013.12.19

申请国别(地区):

CR

年份:

2014

代理人:

摘要：

Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-±4²7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-±4²7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-±4²7 antibody in vivo.

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