GUSAROVA, VIKTORIA,MURPHY, ANDREW J.,GROMADA, JESPER,GUO, DAYONG
申请号：
HK19100854
公开号：
HK1258506A1
申请日:
2019.01.17
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
Non-human animals, and methods and compositions for making and using the same, are provided, wherein said non-human animals comprise a humanization of an Angiopoietin-like protein 8 (ANGPTL8) gene. Said non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous ANGPTL8 locus so that said non-human animals express a human ANGPTL8 polypeptide.
