Biopharm Gesellschaft zur biotechnologischen Entwicklung von Pharmaka mbH
发明人:
Jens POHL,Frank PLOEGER
申请号：
US13721513
公开号：
US20130309221A1
申请日:
2012.12.20
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention relates to the production and use of pharmaceutical growth factor compositions with novel characteristics, e.g. improved solubility and controlled release characteristics under physiological conditions. Said compositions of one or more precursor proteins of growth factors of the GDF family provoke morphogenic effects such as for example growth, differentiation, protection and regeneration of a variety of tissues and organs, e.g. bone, cartilage, tendons, ligaments, nerves and skin. The invention can be advantageously used for the healing of tissue-destructive injuries and for the prevention or therapy of degenerative disorders.
