This invention provides a skin renewal growth factor, wherein the skin renewal growth factor is obtained by separating platelets from pig blood first, which is then activated by an activator and followed by centrifugation and freeze-drying processes. The present invention further provides a method to promote skin cell regeneration by using the aforesaid skin renewal growth factor. The present invention also provides a method to inhibit secretion of melanin by using the aforesaid skin renewal growth factor. The present invention further provides a skin care product containing the aforementioned skin renewal growth factor for skin care. The skin renewal growth factor of this invention can be stored for a long time, and can be produced from pig blood in large scale it is quite economically viable and can be used in skin care product for skin care to promote the regeneration of skin cells and to inhibit melanin secretion.本發明提供一種皮膚更新生長因子,該皮膚更新生長因子係由豬全血分離出血小板後,藉由活化劑激活血小板,並歷經離心以及冷凍乾燥而得之;本發明更提供一種使用如前述之皮膚更新生長因子促進皮膚細胞再生之方法;本發明再提供一種使用如前述之皮膚更新生長因子抑制黑色素分泌之方法;本發明再提供一種用於皮膚保養之保養品,其包含前述皮膚更新生長因子。本發明之皮膚更新生長因子可長時間保存,且由豬血獲得利於大規模製造,相當具有經濟效益,並可用於保養皮膚的保養品,藉以促進皮膚細胞再生以及抑制黑色素分泌。