Derivatives pharmaceutically acceptable thereof, or a salt thereof or a compound of formula (I) are provided: wherein, A represents a chemical moiety represented by the general formula (II) formula, Y and X is , is selected from the group consisting of (R 5) from (R 6) CH 2, CH C or (R 5) independently, R 1 is optionally heteroatom substituted and aryl and alkyl, optionally substituted is selected from the group consisting of arylalkyl, R 2 is selected from the group consisting of NR 7 R 8, or heteroaryl which may be substituted or aryl which may be substituted, R 3 is hydrogen, halogen, hydroxyl , is selected from the group consisting of nitrile or aminosulfonyl optionally substituted amino, can be optionally substituted alkyl, optionally substituted alkoxy, aryloxy, optionally substituted, hydrogen, R 4 is optionally substituted Good sulfamoyl, and optionally substituted sulfonyl, the optionally substituted acyl, optionally substituted heterocycloalkyl alkyl, optionally substituted cycloalkyl, and optionally substituted alkyl, optionally substituted is selected from the group consisting of optionally substituted heteroaryl and optionally substituted aryl and alkyl, aryl which may, be substituted, is an alkyl which may be substituted respectively, R 6 and R 5 is R 7 and It may be the same or different, R 8 is substituted aryl or optionally substituted aryl alkyl, optionally substituted cycloalkyl alkyl, optionally substituted alkyl, optionally substituted hydrogen, optionally substituted respectively represents a good heteroaryl be, is n, is 0, 1, 2 or 3 it is 2 or 0,1 o is however, when o is 0, 1, 2 or 3 n is When o is 1, n is 1 or 2. There is also provided a pharmaceutical composition comprising said compound. These compounds are useful in the treatment of various diseases, including arrhythmias.式(I)の化合物もしくはその塩またはこれらの製薬上許容されうる誘導体が提供される:式中、Aは、一般式(II)で表される化学部分を表し;式中、XおよびYは、独立してCH2,CH(R5)またはC(R5)(R6)からなる群より選択され、R1は、置換されていてもよいアリールアルキル、および置換されていてもよいヘテロアリールアルキルからなる群より選
