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New arylamides substituted by benzoxazolone
专利权人:
F. Hoffmann-La Roche AG
发明人:
DILLON, Michael,CHEN, Li,FENG, Lichun,YANG, Minmin
申请号:
ES10729825
公开号:
ES2593405T3
申请日:
2010.06.15
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
A compound of formula III: ** Formula ** or its pharmaceutically acceptable salts, wherein: R1 is: methyl; R2 is: cyclopropyl; 2-methoxy-1-methyl-ethyl; 2-hydroxy-1-methyl-ethyl; 5-methylpyrazin-2-yl-methyl; 1-pyrazin-2-yl-ethyl; pyrimidin-5-yl-methyl; 6-methyl-pyridazin-3-yl-methyl; pyridazin-3-yl-methyl; 5-methyl-pyrimidin-2-yl-methyl; or 2-methylpyrimidin-5-yl-methyl; X is: -N-; n is from 0 to 2; Cast-; R8 is: C1-6 alkyl; C1-6 alkoxy; C1-6 alkyl sulfonyl; halo C1-6 alkyl; or haloUn compuesto de fórmula III:**Fórmula** o sus sales farmacéuticamente aceptables, en la que: R1 es: metilo; R2 es: ciclopropilo; 2-metoxi-1-metil-etilo; 2-hidroxi-1-metil-etilo; 5-metilpirazin-2-il-metilo; 1-pirazin-2-il-etilo; pirimidin-5-il-metilo; 6-metil-piridazin-3-il-metilo; piridazin-3-il-metilo; 5-metil-pirimidin-2-il-metilo; o 2-metilpirimidin- 5-il-metilo; X es: -N-; n es de 0 a 2; Y es: -O-; R8 es: alquilo C1-6; alcoxi C1-6; alquil C1-6-sulfonilo; halo-alquilo C1-6; o halo.
来源网站:
中国工程科技知识中心
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