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Compound having affinity for amyloid
专利权人:
Shigeyuki Tanifuji
发明人:
Shigeyuki Tanifuji,Daisaku Nakamura,Shinya Takasaki,Yuki Okumura
申请号:
US12312867
公开号:
US08207189B2
申请日:
2007.08.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound represented by the following formula or a salt thereof:wherein each of A1, A2, A3 and A4 independently represents a carbon or nitrogen, R1 is a radioactive halogen substituent, R2 is a group selected from the group consisting of hydrogen, a hydroxyl group, a methoxy group, a carboxyl group, an amino group, an N-methylamino group, an N,N-dimethylamino group and a cyano group, and p is an integer of 0 to 2, provided at least one of A1, A2, A3 and A4 represents a carbon, and R1 binds to a carbon represented by A1, A2, A3 or A4, is effective as an image diagnosis probe targeting amyloid. A diagnostic agent for Alzheimers disease contains the compound.
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