TANIFUJI, SHIGEYUKI,HAYASHI, AKIO,NAKAMURA, DAISAKU,TAKASAKI, SHINYA,STOREY, ANTHONY EAMON,BOUVET, DENIS RAYMOND CHRISTOPHE
申请号:
EP07767329
公开号:
EP2042501A4
申请日:
2007.06.21
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1): or a salt thereof, wherein R 1 is a group selected from hydrogen, hydroxyl group, carboxyl group, sulfate group, amino group, nitro group, cyano group, an alkyl substituent with one to 4 carbon atoms or an alkoxy substituent with one to 4 carbon atoms R 2 is a radioactive halogen substituent and m is an integer of 0 to 2, and a low-toxic diagnostic agent for Alzheimers disease comprising a compound represented by the above formula or a salt thereof is also provided.