Nakamura, Daisaku,Hayashi, Akio,Takasaki, Shinya,Tanifuji, Shigeyuki,Storey, Anthony Eamon,Bouvet, Denis Raymond Christophe
申请号：
AU2007261985
公开号：
AU2007261985B2
申请日:
2007.06.21
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Disclosed is a compound having affinity for amyloid and satisfactorily rapid clearance from a normal tissue and reduced in toxicity including mutagenicity. Specifically disclosed are: a compound represented by the formula (1) and a salt thereof； and a low-toxic diagnostic agent for Alzheimer's disease comprising the compound or the salt thereof. (1) wherein R represents a group selected from a hydrogen, a hydroxyl group, a carboxyl group, a sulfate group, an amino group, a nitro group, a cyano group, an alkyl substituent group having 1 to 4 carbon atoms and an alkoxy substituent group having 1 to 4 carbon atoms； R represents a radioactive halogen substituent group； and m represents an integer ranging from 0 to 2.
