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Process for the preparation of yeast microcapsules
专利权人:
Gnosis S.p.A.
发明人:
Hermes Pagani,Roberto Xaiz,Simona Riboldi
申请号:
DE602005004114
公开号:
DE602005004114T3
申请日:
2005.02.18
申请国别(地区):
DE
年份:
2016
代理人:
摘要:
Disclosed is a process for the preparation of probiotic yeasts in whole, live, non-freeze-dried cells in the form of microcapsules, which comprises: a) centrifugation or microfiltration of yeast cells from the culture broth; b) washing with water of the yeast cells and resuspension in sterile water; c) possibly, the addition to the suspension obtained in b) of bentonite, kaolin, silica, microcellulose, lecithinated sodium, and/or natural or hydrogenated vegetable or animal oils; d) drying at low pressure of the mixture obtained in c) at a temperature of between 20°C and 40°C to an H 2 O content of between 0.5 and 5%; e) addition of excipients to the dried substance and direct compression of the mixture; f) granulation of the tablets obtained in e); g) coating of the granules obtained in f) with molten wax.
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