Antibodies and other molecules that bind B7-H1 and PD-1

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专利权人:

Inc.;Amplimmune

发明人:

Langermann, Solomon,Liu, Linda,Marshall, Shannon,Yao, Sheng

申请号：

AU2012245477

公开号：

AU2012245477A1

申请日:

2012.04.19

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to antibodies and their antigen-binding fragments and to other molecules that are capable of immunospecifically binding to B7-H1 or PD-1. In some embodiments such molecules are additionally capable of modulating the ability of B7-H1 or B7-DC to bind to PD-1 or are capable of affecting the signaling activity of the B7-H1 or PD-1. The invention additionally concerns the uses of such molecules in the diagnosis and treatment of cancer and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/