ANTICORPS ET AUTRES MOLECULES QUI SE LIENT A B7-H1 ET A PD-1

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专利权人:

AMPLIMMUNE; INC.

发明人:

LANGERMANN, SOLOMON,LIU, LINDA,MARSHALL, SHANNON,YAO, SHENG

申请号：

CA2833636

公开号：

CA2833636A1

申请日:

2012.04.19

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The present invention relates to antibodies and their antigen-binding fragments and to other molecules that are capable of immunospecifically binding to B7-H1 or PD-1. In some embodiments such molecules are additionally capable of modulating the ability of B7-H1 or B7-DC to bind to PD-1 or are capable of affecting the signaling activity of the B7-H1 or PD-1. The invention additionally concerns the uses of such molecules in the diagnosis and treatment of cancer and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/