The present invention relates to a disposable and removable cartridge (1) configured to cooperate with a wearable support device, said wearable support device comprising means to be secured to the skin of a subject, at least one connection track and at least one first positioning means said disposable and removable cartridge (1) comprising: at least one microneedle (11) a sensing area (12) a microfluidic circuit in fluid communication with said at least one microneedle (11) and with said sensing area (12) at least one sensor (121) adapted to monitor at least one parameter of a fluid providing from the patient, in the sensing area (12) a second connection track (123) electrically connected to the at least one sensor (121) at least one second positioning means configured to cooperate with the at least one first positioning means of the support device in such a way that the at least one first connection track of the support device is connected at said at least one second connection track (123) of the disposable and removable cartridge (1), and in such a way the cartridge is releasably secured to the wearable support device. The present invention also relates to a wearable support device corresponding and a system comprising such disposable and removable cartridge (1) and such wearable support deviceLa présente invention concerne une cartouche jetable et amovible (1) configurée pour coopérer avec un dispositif de support pouvant être porté, ledit dispositif de support pouvant être porté comprenant des moyens à fixer à la peau dun sujet, au moins une voie de connexion et au moins un premier système de positionnement ladite cartouche jetable et amovible (1) comprenant : au moins une micro-aiguille (11) une zone de détection (12) un circuit microfluidique en communication fluidique avec ladite au moins une micro-aiguille (11) et avec ladite zone de détection (12) au moins un capteur (121) conçu pour surveiller au moins un paramètre dun fluide fourni par le patient, dan
