Relating to compounds of formula (i): able to modulate the activity of Histone demethylases (hdmes), which are useful for the Prevention and \/ or treatment of cancer, etc., and formulations and Methods of using such compounds. Where: q is - ch = nr12, etc. - alquileno C1 C8, arylene, etc. and it is - C1 C8 h, alkyl, etc. r1 is H, alkyl C8 C1 -, etc.R12 is alkyl C1 - C10, alquinilo C2 C10, etc. Preferred compounds are: N ({- {[2 - [4 - (Diethylamino) methyl] amino} Butyl) pyridin-4-yl] - methyl - trifluoracetamida 2,2,2} {[2 - (4 - [(dimethylamino) butyl methyl] amino}) metanamina pyridin-4-yl]Referida a compuestos de la formula (I): Capaces de modular la actividad de histona desmetilasas (HDMEs), los cuales son utiles para la prevencion y/o tratamiento de cancer, etc., y formulaciones y metodos de uso de dichos compuestos. Donde: Q es -CH=NR12, etc. A es -alquileno C1-C8, arileno, etc. Y es -H, alquilo C1-C8, etc. R1 es -H, alquilo C1-C8, etc. R12 es alquilo C1-C10, alquinilo C2-C10, etc. Los compuestos preferidos son: N-{[2-({[4-(dietilamino)butil]amino}metil)piridin-4-il]metil}-2,2,2-trifluoracetamida [2-({[4-(dimetilamino)butil]amino}metil)piridin-4-il]metanamina
