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Phosphonate derivatives featuring a fused heterocycling ring such as purine for treating cancer and other cellular proliferation diseases
专利权人:
INC.;GILEAD SCIENCES
发明人:
BIRKUS, GABRIEL,RAY, ADRIAN, S,TUMAS, DANIEL,WATKINS, WILLIAM, J
申请号:
NZ58746409
公开号:
NZ587464A
申请日:
2009.02.19
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
A compound having structure (4) wherein each Ra independently is C1-C4 alkyl, or benzyl, each Rb independently is C1-C4 alkyl, R10 is C1-C8 alkyl, or C2-C8 alkenyl, or C2-C8 alkynyl, wherein C1-C8 alkyl is optionally substituted by one C1-C4 alkoxy group and/or pharmaceutically acceptable salts or enriched optical isomers thereof. These compounds are provided for use in the treatment of tumors cancer and the prophylaxis or treatment of viral infections.
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