ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.
发明人:
FERRIGNO, FEDERICA,JONES, PHILIP,MURAGLIA, ESTER,ONTORIA ONTORIA, JESUS MARIA,SCARPELLI, RITA,SCHULTZ-FADEMRECHT, CARSTEN
申请号:
CA2641933
公开号:
CA2641933C
申请日:
2007.02.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to compounds of formula (I), andpharmaceutically acceptable salts and tautomers thereof. Compounds of thepresent invention are inhibitors of histone deacetylase (HDAC) and are usefulfor treating cellular proliferative diseases, including cancer. They are alsouseful for treating neurodegenerative diseases, mental retardation, 10schizophrenia, inflammatory diseases, restenosis, immune disorders, diabetes,cardiovascular disorders and asthma.