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Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors
专利权人:
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti SpA
发明人:
Ferrigno, Federica,Scarpelli, Rita,Schultz-Fademrecht, Carsten,Muraglia, Ester,Jones, Philip,Ontoria Ontoria, Jesus Maria
申请号:
AU2007216323
公开号:
AU2007216323B2
申请日:
2007.02.14
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts and tautomers thereof. Compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. They are also useful for treating neurodegenerative diseases, mental retardation, 10 schizophrenia, inflammatory diseases, restenosis, immune disorders, diabetes, cardiovascular disorders and asthma.
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