The invention provides use of a compound of formula I:(see formula I)for prophylaxis or treatment of a condition that is leukemia, malignantmelanoma,Ewing's sarcoma, breast cancer, prostate cancer, neuroblastoma, glioma,myeloma, lymphoma, a gastrointestinal tumor, a gynecological cancer or lungcancer, cells of which express insulin-like growth factor-1 receptor, and theinvention also provides use of a compound of formula I for treating aconditionwhich is psoriasis, arteriosclerosis, restenosis after coronary angioplasty oracromegaly.