CHIMERIC ANTIGEN RECEPTORS TARGETING EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III

• 收藏
• 分享

专利权人:

发明人:

申请号：

EP17701190.5

公开号：

EP3405481A1

申请日:

2017.01.10

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention provides the Chimeric antigen receptor (Chimeric Antigen Receptor, CAR) of specific binding EGFRvIII (EGF-R ELISA variant III). The invention further relates to the immunocytes of the transformation comprising this kind of CAR, the nucleic acid for encoding CAR and preparation method thereof, the immunocyte and nucleic acid of transformation. The invention further relates to the treatment methods that the pathology for using the immune cell therapy EGFRvIII- of these CAR and transformation to mediate includes cancer as such as neuroblastoma.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/