ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.
发明人:
JONES, PHILIP,ONTORIA ONTORIA, JESUS MARIA,SCARPELLI, RITA,INGENITO, RAFFAELE,SCHULTZ-FADEMRECHT, CARSTEN
申请号:
CA2633351
公开号:
CA2633351C
申请日:
2006.12.21
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to compounds of formula (I): andpharmaceutically acceptable salts and tautomersthereof. Compounds of the present invention are inhibitors of histonedeacetylase (HDAC) and are useful for treating cellularproliferative diseases, including cancer. They are also useful for treatingneurodegenerative diseases, mental retardation, schizophrenia,inflammatory diseases, restenosis, immune disorders, diabetes, cardiovasculardisorders and asthma.