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METHODS FOR IMAGING BONE PRECURSOR CELLS USING DUAL-LABELED IMAGING AGENTS TO DETECT MMP-9 POSITIVE CELLS
专利权人:
Elizabeth A. Davis
发明人:
Elizabeth A. Davis,Alan R. Davis,Eva M. Sevick-Muraca,Sunkuk Kwon
申请号:
US14115990
公开号:
US20140178293A1
申请日:
2012.05.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention includes embodiments for methods and compositions that identify the presence of or risk for developing heterotopic ossification, particularly prior to mineralization of the bone. In particular embodiments, MMP-9 and/or MMP-2 agents comprising dual imaging moieties are used to identify patterns of MMP-9 and/or MMP-2 localization, respectively, that is then predictive of heterotopic ossification.
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中国工程科技知识中心
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