Kwang Yeol Lee,Min Sik Kim,Taek Hoon Kim,Ngoc Phan Vu
申请号:
US14782481
公开号:
US20160051707A1
申请日:
2013.04.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a magnetic resonance imaging (MRI) contrast agent, particularly a metal oxide nanoparticle-based T1-T2 dual-mode MRI contrast agent that can be used not only as a T1 MRI contrast agent but also as a T2 MRI contrast agent, and a method for producing the same. The metal oxide nanoparticle-based T1-T2 dual-mode MRI contrast agent can provide more accurate and detailed information associated with disease than single MRI contrast agent by the beneficial contrast effects in both T1 imaging with high tissue resolution and T2 imaging with high feasibility on detection of a lesion.