LEE, HYOUNG IK,李垧一,李垧一,LE HIR DE FALLOIS, LOIC PATRICK,洛伊克 派屈克 勒希迪伐洛伊斯,洛伊克 派屈克 勒希迪伐洛伊斯,TIMMONS, PHILIP REID,飞利浦 莱德 提蒙斯,飛利浦 萊德 提蒙斯,CAWTHORNE, WILLIAM GLENN JR.,威廉 葛兰 考索恩 二世,威廉 葛蘭 考索恩 二世,DE LEON, ADALBE
申请号：
TW096124519
公开号：
TWI396683B
申请日:
2007.07.05
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (1):wherein: R1is hydrogen, cyano, halogen, R8, formyl,-C(O)R8, -C(O)OR8,-C(O)NR9R10, or -C(S)NH2 R2is R8or-S(O)mR11 R3is methyl, ethyl or C1-C4haloalkyl R4, R5and R7are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro R6is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro,-C(O)R12,-S(O)nR12or SF5 Z is a nitrogen atom or C-R13 R8is alkyl, haloalkyl, cycloalkyl or halocycloalkyl R9is hydrogen, alkyl, haloalkyl or alkoxy R10is hydrogen, alkyl, haloalkyl or alkoxy R11is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl R12is alkyl or haloalkyl R13is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy m is 0, 1 or 2 and n is 0, 1 or 2 or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.本發明提供式(I)之1-芳基-5-烷基吡唑化合物:其中:R1為氫、氰基、鹵素、R8、甲醯基、-C(O)R8、-C(O)OR8、-C(O)NR9R10或-C(S)NH2;R2為R8或-S(O)mR11;R3為甲基、乙基或C1-C4鹵烷基;R4、R5及R7獨立地為氫、鹵素、烷基、鹵烷基、氰基或硝基;R6為鹵素、烷基、鹵烷基、烷氧基、鹵烷氧基、氰基、硝基、-C(O)R12、-S(O)nR12或SF5;Z為氮原子或C-R13;R8為烷基、鹵烷基、環烷基或鹵環烷基;R9為氫、烷基、鹵烷基或烷氧基;R10為氫、烷基、鹵烷基或烷氧基;R11為烷基、鹵烷基、烯基、鹵烯基、炔基、鹵炔基或環烷基;R12為烷基或鹵烷基;R13為氫、鹵素、氰基、硝基、烷基、鹵烷基、烷氧基或鹵烷氧基;m為0、1或2;且n為0、1或2;或其鹽,製備式(I)化合物之方法及此等化合物防治體外寄生蟲、體內寄生蟲及害蟲之用途。
