The present invention relates to a composition comprising about 0.001% to about 1% by weight of cannabinoids or derivatives thereof, based on the total weight of the mixture, and an alcohol, with water and other compositions as the balance of the weight. The present invention also relates to an alcoholic beverage containing between about 0.001% to about 1% (wt/wt) cannabinoids and derivatives thereof, between about 2% to about 45% (wt/wt) of alcohol, with water, fermentation byproducts, emulsifiers, and flavor enhancers composing the balance of the total weight. The invention also discloses methods to prepare these compositions, and methods of use to minimize adverse effects from alcohol consumption.