BAUMANN KARLHEINZ,LLIMBERG ANJA,THOMAS ANDREW,GREEN LUKE,LUEBBERS THOMAS
申请号：
ZA201305322
公开号：
ZA201305322B
申请日:
2013.07.15
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
The present invention relates to compounds of formula I hetaryl I, hetaryl II, R1, R2, R3, Y, m, and o or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of &bgr；-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
