ILKOW, Carolina Solange,LEBOEUF, Fabrice,BELL, John Cameron,DIALLO, Jean-simon,ARULANANDAM, Rozanne
申请号:
EP14811047
公开号:
EP3008176A4
申请日:
2014.06.16
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.