ILKOW, CAROLINA SOLANGE,LE BOEUF, FABRICE,BELL, JOHN CAMERON,DIALLO, JEAN-SIMON,ARULANANDAM, ROZANNE
申请号:
CA2915045
公开号:
CA2915045A1
申请日:
2014.06.16
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.